[Comparison of the mean level of C3 and C4 complements in pre-eclamptic patients and normal pregnancy]

Hypertension is still an important cause of mortality in mother, fetus and neonate. Up to 25% of perinatal mortality in developing countries is due to hypertension. The role of immunologic factors in development of preeclampsia is increasing. Decreased level of C3 and C4 complements in preeclamptic patients has been documented in some studies. The goal of this study is to compare the level of C3 and C4 in patients with normal pregnancy versus those with pre-eclampsia. This cross-sectional study was performed during one year, among pregnant women with a gestational age of more than 20 weeks and blood pressure over 140/90 mmHg plus proteinuria over 300 mg in 24h-urine or over 30 mg/dl in random urine. We selected 23 preeclamptic cases and 34 controls. Mean level of C3 in pre-eclamptic patients was 98.8 +/- 25.82 mg/dl and 112.5 +/- 29.03 mg/dl in controls [p<0.005]. Mean level of C4 in preeclamptic patients was 27.9 +/- 10.62 mg/dl and 35 +/- 11.25 mg/dl in controls [p<0.05]. In this study, the level of C3 and C4 in pre-eclamptic patients was lower than in those without pre-eclamsia. It is suggested that decreased level of these complements can be considered as a predictive factor of preeclampsia. More studies are warranted in this field

Determining the efficacy of erythromycin ointment 0.5% in protection of conjunctivitis in neonates under phototherapy with eye patches

Ophthalmia neonatorum is a form of conjunctivitis that occurs in infants younger than 4 weeks of age. It is the most common eye disease in newborns. It presents as the inflammation of mucous membrane lining posterior layer of eyelids and bulbar part of eyeball except cornea. It's complications are corneal ulcer, corneal perforation and blindness. The aim of this randomised clinical trial was to investigate the effect of erythromycin ointment 0.5% to prevent the incidence of conjunctivitis in icteric neonates who were under phototherapy with eye patches. A total of 200 cases of icteric newborns in Javaheri hospital who admitted for phototherapy were considered. Neonatal conjunctivitis was not correlated with gestational age, duration of admission, type of delivery, and weight. It was not associated with erythromycin use, however, there was a significant association between conjunctivitis and age of newborn. Results showed that erythromycin ointment is not useful for protecting conjunctivitis in neonates under phototherapy with eye patches

[Evaluation of lidocaine and bupivacaine in post operation pain after abdominal hysterectomy]

Post operation pain is seen in 30-70 percent of patients. Using local anesthetic is a safe, easy and cheap method for post opration pain management. In this study, the effects of lidocaine and bupivacaine lavage on post operation pain are assessed. In this double blind randomized control clinical trial, 90 healty women between 15-60 years old randomly allocated in 3 groups, lidocaine, bupivacaine and normal salin. After abdominal hysterectomy the medicine or placebo [in uniform package] is Administered in peritoneal cavity by surgeon and, 0, 2,6,12,24 and 48 hours after the surgery, the rate of pain was checked. Consumption of morphin and frequency of vomiting were measured and compared between groups using SPSS 12 software. Post operational pain relief was significantly lower in lidocaine group compared with bupivacaine and normal saline, however, morphin consumption and frequency of vomiting were the same in three groups. Based on the results, it can be concluded that intraperitoneal lidocaine provides significant pain relief for 12 hours after abdominal hysterectomy